Mygenia Cardiac Health Risk Assessment

What is this test for?

Mygenia cardio panel consists of a series of genetic sequencing tests specified for detecting inherited risk that leads to Cardiac Death.

What is “Cardiac death”?

Cardiac death is the generalized term representing deaths caused by heart or cardiac failure. In Hong Kong, it is ranked the 3rd top killer in 20131. Sudden Cardiac Death (SCD), being one major example, can go as far to claim one’s life in their prime year without any precautionary symptoms. It is a very serious situation in Hong Kong for it accounts for over one-third of the all cardiac deaths.

Around three-quarters of SCD cases are caused by coronary heart disease2. Others are mostly unexplained. With recent advancement of technology, scientists recognize a high association of these cases with genetic factors. Inherited Cardiomyopathies (CM) and Sudden Arrhythmia Death Syndrome (SADS) fall under this category.

Cardiac death is dangerous and silent

NO SIGNS OR SYMPTOMS

When it happens, it can claim a person’s life immediately without having enough time to react.

CAN OCCUR IN MOST HEALTHY BEINGS

There are cases of SCD occurring in young and healthy adults, even children

SIMILAR TO MUSCLE PAIN

Heart attack is often misinterpreted as minor muscle pain

Who should consider this test?

Family history of any heart diseases

- Genetic associated risk

- Patients with family history has 5.3 folds increased risk

High risk life styles

- Smoking

- Stress

- Poor diet

Experienced muscle pain around the chest

- Pain may be associated with the heart instead

 

What should I do if I am at risk?

IMMEDIATELY CONSULT YOUR DOCTOR FOR GENETIC TEST

Test for genetic factors for cardiomyopathies (CM) and sudden arrhythmia death syndrome (SADS) - ie. Mygenia Cardio Panel

TAKE PREVENTIVE MEASURES

Early identification of genetic risk can prevent SCD from happening with proper preventive measures - eg. Drug intervention

CLOSELY MONITOR WITH REGULAR CHECK-UP

Monitor your heart condition and identify any abnormality before it is too late

AVOID HIGH RISK LIFE STYLE

It is always advisable to have a good habit for healthy life style

Test Specifications

Test Code
Methodology
Specimen Requirements
Turnaround Time
RHE
Next generation sequencing (NGS)
6 mL blood in EDTA tube/ buccal swab
30 days
RHS
Next generation sequencing (NGS)
6 mL blood in EDTA tube/ buccal swab
30 days

Precautions before testing

No transfusion of blood 1 month before the test

No organ Transplantation

What should I do if my test results are positive?

Please consult your physicians or genetic counselor for professional advices before taking any actions.

Share the result with family members.

How to get started

Our tests must be ordered by a doctor. Ask your doctor if a Mygenia test is right for you. We can help you find a doctor if you don’t have one.

I have a doctor
References
  1. http://www.chp.gov.hk/en/data/4/10/27/380.html
  2. Deo, R. et al. Epidemiology and genetics of sudden cardiac death. Circulation. 2012; 125(4), 620-637.
  3. Elliott, P. M.,et al. Sudden death in hypertrophic cardiomyopathy: identification of high risk patients. Journal of the American College of Cardiology, 2000; 36(7), 2212-2218.
  4. Marian AJ, et al. Molecular genetics of hypertrophic cardiomyopathy. Annu Rev Med. 1995; 46:213-22.