Mygenia Cancer Health Risk Assessment Test

Why do we need cancer risk assessment?

Cancer has always ranked the number one killer worldwide and everyone knows that. However, not everyone knows that cancer can be predicted and prevented. Identifying the inheritance of cancer genes opens up chances for early preventive measures.

How is family history related to cancer?

Cancer is a common disease. There are many factors that trigger cells in becoming cancerous: aging, poor life style, poor diet, or pollution can all lead to cancer. Normally, people are born with the ability to repair and control damages caused by these factors. These natural abilities are coded in some specific genes known as the damage-controlling genes. Hereditary cancers occur when we born with one or more of these genes mutated. In other words, these cancer-causing gene mutations can be inherited.

Family history is important in determining the chance of inheritance. Everyone inherits two copies of the same gene from our parents, one from father and the other from mother. Most of the time, both inherited copies are normal. If one of the parents has a mutation in these genes, then it means that there is a 1 in 2 chance (50%) of inheriting the same mutation. Although, of all cancer cases, only about 10% are hereditary, it is still important to find out your hereditary risk so that early prevention can be made.

How can Mygenia cancer panel test help you assess the cancer risk?

Mygenia cancer panel test covers 200 cancer related diseases:

  • Breast & Ovarian
  • Colorectal
  • Gastric
  • Kidney
  • Pancreatic
  • Prostate
  • Paraganglimo
  • Neuroblastoma
  • Neurofibromatosis
  • Retinoblastoma
  • Skin
  • Endocrine
  • Head & Neck

Patients can either choose to screen for all 200 cancer types (test code OFC) or 1 cancer type only (test code OF1). We also offer a follow-up test for family members (test code OFF). This enables physicians in selecting the most optimal solution for the inherited cancer management as well as providing risk assessment for individuals with family history.

Who should do the test?

  • Multiple family members affected with the same cancer (eg. breast cancer) or related cancers (eg. breast and ovarian cancer, or colon and uterine cancer)
  • Two or more first-degree relatives with rare tumors (eg. sarcoma in both a brother and a sister)
  • Geographic or ethnic populations known to be at high risk of hereditary cancers (e.g., Ashkenazi Jews heritage and BRCA1 / BRCA2 mutations)
  • Family history of unique tumor combinations (eg. sarcoma, breast and brain in the same family)

Test Specifications

Test Code
Methodology
Specimen Requirements
Turnaround Time
RCL
Next generation sequencing (NGS)
6 mL blood in EDTA tube/ buccal swab
30 days
RCM
Next generation sequencing (NGS)
6 mL blood in EDTA tube/ buccal swab
30 days
RCS
Next generation sequencing (NGS)
6 mL blood in EDTA tube/ buccal swab
30 days

Precautions before testing

No transfusion of blood 1 month before the test

No organ Transplantation

What should I do if my test results are positive?

Please counsel your physicians or genetic counselor for professional advices before taking any actions.

Sharing the result with family members.

How to get started

Our tests must be ordered by a doctor. Ask your doctor if a Mygenia test is right for you. We can help you find a doctor if you don’t have one.

I have a doctor
References
  1. Mauer, Caitlin B., et al. "The integration of next-generation sequencing panels in the clinical cancer genetics practice: an institutional experience." Genetics in Medicine 16.5 (2013): 407-412.
  2. http://www.cancer.gov/cancertopics/pdq/genetics/risk-assessment-and counseling/HealthProfessional/Page1
  3. http://www.breastcancer.org/risk/factors/genetics